Oropharyngeai decontamination in combination with gastrointestinal excitomotor for preventing hospital-acquired lower respiratory tract infection in elderly inpatients
10.3760/cma.j.issn.1674-2397.2010.05.013
- VernacularTitle:口腔脱污染联合胃肠动力药物预防老年人医院获得性下呼吸道感染的临床研究
- Author:
Sheng WU
;
Xuanding WANG
;
Xiaojun LU
;
Zhixue GUO
- Publication Type:Journal Article
- Keywords:
Elderly;
Hospital-acquired lower respiratory tract infection;
Oropharyngeal decontamination;
Gastrointestinal excitomotor
- From:
Chinese Journal of Clinical Infectious Diseases
2010;03(5):297-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of oropharyngeal decontamination combined with gastrointestinal excitomotor in preventing hospital-acquired lower respiratory tract infection(HALRTI)in elderly inpatients. Methods Totally 110 elderly inpatients with high risks of HALRTI were randomized into intervention group and control group. Patients of the intervention group were administrated by cetylpyridinium chloride gargle twice daily for gargling(20 mL for each), combined with moshabili three times daily orally(5 mg for each). Exact Sig. l-sided was performed to compare the occurence of HALRTI,and Spearman test was performed to evaluate the correlation between positive rate of the phyarynx swabs and the hospitalized time. SPSS 12.0 software was used for statistical analyzing. Results Patients suffered from HALRTI were 1 case(2.00%)in intervention group and 7 cases(13.73%)in control group respectively,and the difference was of statistical significance(P ＜ 0.05). As hospitalized time went on, the positive rate of the phyarynx swabs microbial culture in the control group increased(r = 0.450, P ＜ 0.05), while the intervention group showed no significant change during the whole intervention time(r = -0.023, P ＞0.05). Conclusion The combined intervention of oropharyngeal decontamination with the gastrointestinal excitomotor may be beneficial to elderly inpatients with high risk of HALRTI in the prevention of HALRTI.
