Effects of low-concentration heparin sodium on preventing thrombophlebitis in patients with peripherally inserted central catheter
10.3760/cma.j.issn.1674-635X.2010.01.015
- VernacularTitle:低浓度肝素稀释液对经外周静脉置入中心静脉导管置管期间血栓性静脉炎的预防效果
- Author:
Liling XIE
- Publication Type:Journal Article
- Keywords:
Peripherally inserted central catheter;
Heparin sodium dilution;
Thrombophlebitis
- From:
Chinese Journal of Clinical Nutrition
2010;18(1):56-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of low-concentration heparin sodium (LCHS) on preventing thrombophlebitis in patients with peripherally inserted central catheter (PICC). Methods Totally 287 patients who received PICC from 2007 to 2009 in our department were divided into LCHS group ( n = 128 ), in which the patients had no coagulation disorders or other blood diseases and the used drugs were compatible with heparin sodium, and control group ( n = 159). In the LCHS group, LCHS ( 10 U/ml) was used for irrigation and sealing of the catheter with positive pressure. In the control group, 0. 9% normal saline was used for the same procedures. Changes of the clinical manifestations of phlebitis and the values of plasma fibrinogen in both two groups were observed.Results In LCHS group, 21 patients had obvious clinical manifestations of phlebitis, among whom 8 patients met the diagnostic criteria of thrombophlebitis. On the contrary, in control group, 38 patients had obvious clinical manifestations of phlebitis ( P ＜ 0. 05 ), among whom 31 patients met the diagnostic criteria of thrombophlebitis ( P ＜0. 001 ). The changes of plasma fibrinogen were also significantly different between these two groups ( P ＜ 0. 001 ).Conclusion LCHS can prevent thrombophlebitis in patients with PICC who have no coagulation disorder or other blood diseases and the used drugs are compatible with heparin sodium.
