ABO incompatible liver transplantation
10.3760/cma.j.issn.1007-8118.2010.10.008
- VernacularTitle:供受体ABO血型不合肝移植
- Author:
Xinguo CHEN
;
Fengdong WU
;
Zhaojie GUAN
;
Zhongyang SHEN
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Blood type;
ABO incompatible
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(10):742-744
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the treatment of ABO-incompatible orthotopic liver transplantation. Methods Nine cases of ABO-incompatible liver transplantation performed in our hospital were analyzed retrospectively. Plasma exchange was done before the operation in 1 case. Hepatic artery and biliary duct anastomosis were performed by the microvascular technique. Splenectomy was done during operation in 5 cases. The immunosuppressive protocol included a quadruple drug therapy. Blood oxygen saturation was maintained above 95% and anticoagulant therapy was performed after operation.Results Four patients recovered smoothly without complications. Postoperative complications included acute rejection in 3 patients and biliary nonanastomotic stricture in 4. Three patients died. Conclusion ABO-incompatible orthotopic liver transplantation can be used when the graft is scarce, and should manage to decrease the complications.
