Measurement of serum interleukin-2,soluble interleukin-2 receptor and interleukin-6 of renal allograft recipients
- VernacularTitle:肾移植后血清白细胞介素2、可溶性白细胞介素2受体和白细胞介素6的监测
- Author:
Lijiang SUN
;
Yong CHEN
;
Wujun XUE
- Publication Type:Journal Article
- Keywords:
Kidney/transplantation;
Rejection;
Immunoassay
- From:
Chinese Journal of Organ Transplantation
1998;19(1):10-12
- CountryChina
- Language:Chinese
-
Abstract:
Sequential monitoring of the levels of serum interleukin-2(IL-2),soluble interleukin-2 receptor(sIL-2R)and interleukin-6(IL-6)were conducted in 60 patients for 2 months after renal transplantation.The results showed that the levels of serum IL-2,sIL-2R and IL-6 were increased significantly several days prior to the clinical diagnosis in the patients with acute rejection,which were much higher than those in CsA-induced nephrotoxicity group.The levels of IL-2,slL-2R and IL-6 in the patients with rejection sensible to methylprednisolone came down to the pre-rejection levels several days after the treatment.It was concluded that sequential monitoring of serum IL-2,sIL-2R and IL-6 of renal allograft recipients are helpful for the early diagnosis and differential diagnosis of acute rejection as well as the evaluation of methylprednisolone in the treatment of antirejection.
