Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia
10.3760/cma.j.issn.1008-6706.2010.19.019
- VernacularTitle:不同病原菌致社区获得性肺炎患者中性粒细胞表面补体受体的变化
- Author:
Li LI
;
Shimin FU
;
Xiaoling YU
- Publication Type:Journal Article
- Keywords:
Community-acquired pneumonia;
Complement receptor
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(19):2634-2636
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the different expression of complement receptors on neutrophils between bacterial and viral pneumonia. Methods Fifty-nine patients with CAP were studied prospectively. CR1 ,CR3 were measured by,using flow cytometer. ESR,CRP and WBC were also measured. Results Thirteen patients had pneumococcal pneumonia; 13 patients, A type of infuenza virus pneumonia ;5 patients, atypical pneumonia, and 28 patients, aetiologically undefined pneumonia. The mean expression of complement receptor 1 ( CR1 ) on neutrophils and aetiologically undefined pneumonia was( 19.4 ± 9.8 ) and ( 19.3 ± 8.8), which were significantly higher than those with A type of infuenza virus( t = 6.13,5.09 ,P < 0.01 ). Conclusion The expression of CR1 may be of value as an additional rapid tool in the aetiological diagnosis, bacterial or viral infection of CAP.