Dendritic cells and natural killer cells in relation to tumor cell telomerase:research advances
10.3760/cma.j.issn.1673-422X.2010.10.002
- VernacularTitle:树突状细胞和自然杀伤细胞与肿瘤细胞端粒酶的研究进展
- Author:
Yiwen LI
;
Yuqing XU
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Killer cells,natural;
Neoplasms;
Telomerase;
Immunotherapy
- From:
Journal of International Oncology
2010;37(10):726-728
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells(DC)present telomerase reverse transcriptase(hTERT)to T lymphocytes, stimulating specific reactions of cytotoxic T cells and CD4 + T cells. Researches on the relationship between natural killer(NK)cells and telomerase of tumor cells are scarce. DC and NK cells act together promoting antitumor responses and possibly participate in anti-tumor immune responses with telomerase.