Pathogenesis and targeted therapy of Burkitt's lymphoma
10.3760/cma.j.issn.1673-422X.2010.10.022
- VernacularTitle:伯基特淋巴瘤发病机制及靶向治疗
- Author:
Yu JIANG
;
Xiaojian WANG
- Publication Type:Journal Article
- Keywords:
Burkitt lymphoma;
Apoptosis;
Signal transduction;
Drug resistance
- From:
Journal of International Oncology
2010;37(10):786-789
- CountryChina
- Language:Chinese
-
Abstract:
Burkitt's lymphoma is a highly aggressive and proliferative type of mature B cell nonHodgkin's lymphoma. Therapeutic strategies for Burkitt's lymphoma remain a challenge because of significant toxicities and poor prognosis. Further studies investigating the underlying molecular mechanisms of the carcinogenesis, chemotherapy and drug resistance are needed to improve the treatment of Burkitt's lymphoma.