The antibiotic resistance of Klebsiella pneumoniae in neonatal sepsis

VernacularTitle:新生儿肺炎克雷伯菌脓毒血症细菌的耐药性分析
Author: Can YOU ; Lin ZHANG ; Boli NIE ; Bin HU ; Caizhi HUANG
Publication Type:Journal Article
Keywords: Klebsiella pneumoniae/DE; Sepsis/MI; Drug resistance,bacterial
From: Journal of Chinese Physician 2010;12(10):1337-1340
CountryChina
Language:Chinese
Abstract: Objective To study the drug resistance of neonatal sepsis caused by Klebsiella pneumoniae and provide evidence for drug treatment. Method Retrospectively analysis was conducted on the clinical data and antibiotic resistance of Klebsiella pneumoniae in 50 neonates with sepsis. Results The majority of the 50 cases were infected in hospital. There were 13 ESBLs strains in 50 Klebsiella pneumoniae strains (26%), and the others were negative ESBLs starins (74%). All the strains were multidrug-resistance to the β-lactam antibiotics and only sensitive to few antibiotics such as Imipenem and Amikacin. The sensitive rate was 100%. Conclusions The first selected antibiotic for the treatment of neonatal sepsis caused by Klebsiella pnemoniae was Imipenem or Amikacin.