Effect of hemorrhagic transformation on the outcome in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2010.09.003
- VernacularTitle:出血性转化对急性缺血性卒中患者转归的影响
- Author:
Yuhua CHEN
;
Lina ZHANG
;
Li XU
;
Shoukang CHEN
;
Liang YIN
;
Qiming CHEN
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain ischemia;
Cerebral hemorrhage;
Thrombolytic therapy;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2010;18(9):650-653
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of hemorrhagic transformation (HT) on the outcome of acute ischemic stroke.Methods One hundred and one patients with acute ischemic stroke were divided into cerebral infarction without HT,hemorrhagic infarction (HI),and parenchymal hematoma (PH) according to the CT and/or MRI findings.The modified Rankin Scale (mRS) was used to evaluate the outcome at 3 months after onset,and the good outcome was defined as mRS ≤ 2.The multivariate logistic regression analysis was used to identify the predictors of outcome in patients with acute ischemic stroke.Results There were 53 patients without HT,44 HI,and 4 PH,respectively in 101 patients with acute ischemic stroke.HI (OR =0.07,95% CI0.01-0.30;P ＜0.001),＜65 years (OR =52.94,95% CI9.12-307.27;P＜0.001),and NIHSS score ＜ 15 (OR= 0.63,95% CI 0.50-0.78;P＜0.001) were the independent predictors of good outcome for patients with acute ischemic stroke.Conclusions HI is one of the independent predictors of good outcome at 3 months after acute ischemic stroke.
