Risk factors of hemorrhagic transformation after cerebral infarction
10.3760/cma.j.issn.1673-4904.2010.31.010
- VernacularTitle:脑梗死出血性转化相关危险因素分析
- Author:
Chunhong LIU
;
Qingling MENG
;
Yanfeng SONG
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Risk factors;
Hemorrhagic transformation
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(31):29-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of hemorrhagic transformation (HT) after cerebral infarction. Methods The clinical and neuroimaging data of 100 patients (gender,age-matched)with cerebral infarction and hemorrhagic transformation from January 2005 to January 2010 were analyzed retrospectively. The following factors were listed for single factor analysis: the history of hypertension, diabetes mellitus,admission blood pressure,blood sugar,infarction size,alcohol,smoking,atrial fibrillation,hypercholesterolemia, combined anticoagulant and antiplatelet aggregation therapy. All the above factors were analyzed by chi-square test or t test, and Logistic regression analysis was used to screen out the related risk factors of HT from the potentially related factors. Results Atrial fibrillation (OR =5.483,95%CI:fibrillation,extensive cerebral infarction,blood sugar,high blood pressure at the beginning of the disease,combined anticoagulant and antiplatelet aggregation therapy are the major risk factors of HT. At the same time, the occurrence of HT is the result of the joint effect of multiple factors and multiple mechanisms.
