Clinical analysis of intravascular catheter-related bloodstream infection in neonatal intensive care unit

VernacularTitle:中心静脉导管相关性血流感染21例临床分析
Author: Fang ZHAO ; Bin ZEN ; Xiaoping LIU ; Yuxin ZHOU ; Shuangchuan ZHANG
Publication Type:Journal Article
Keywords: Intravascular catheter; Bloodstream infection; Neonates
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(20):2750-2752
CountryChina
Language:Chinese
Abstract: Objective To find out the clinical characteristics and morbility factors of intravascular catheterrelated bloodstream infection(CRBSI). Methods Totally 21 patients who had CRBSI in neonatal intensive care unit were investigated retrospectively. Results The distribution of CRBSI was higher in very low birthweight preterm infants, gestational age among 28 ～34week, whose intravascular catheter remaining time were obove three weeks. Principal clinical presentation of CRBSI were poor feeding, unaocountable tachycardia, temperature instability, stressed hyperglycemia,refractoriness metabolic acidosis. The most common pathogens were coagulase-negative staphylococci (35.7%), Klebsiella pneumonia, bacilli ( 11.9% ) Staphylococcus aureus (9.5 % ), Pseudomonas aeruginosa( 7. 1% )and Enterobacter cloacae(7.1% ). Conclusions The clinical manifestations of CRBSI were concealment,and reducing the time of inserted central catherization and total parenteral nutrition, strengthening the nutrition of body would provide effective prevention of CRBSI.