Clinical value of alpha-lipoic acid in the management of diabetes mellitus
10.3760/cma.j.issn.1674-635X.2010.05.016
- VernacularTitle:α-硫辛酸在糖尿病治疗中的临床应用价值
- Author:
Li WANG
;
Meiqin CAI
- Publication Type:Journal Article
- Keywords:
Alpha-lipoic acid;
Oxidative stress;
Diabetes mellitus;
Complication;
Clinical application
- From:
Chinese Journal of Clinical Nutrition
2010;18(5):323-326
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress plays an important role in the progression of diabetes mellitus. As a potent antioxidant, alpha-lipoic acid is able to clear free radicals and alleviate oxidative damages and therefore has been widely applied in the clinical management of diabetes mellitus. This article summarizes the clinical application of alpha-lipoic acid in alleviating diabetes mellitus-related oxidative damages, protecting vascular lesions, treating diabetic polyneuropathies, and modulating insulin sensitivity.