Progress on the associated-gene of hereditary spastic paraplegia
10.3760/cma.j.issn.1673-4408.2010.06.024
- VernacularTitle:遗传性痉挛性截瘫相关基因研究进展
- Author:
Wei WEI
;
De WU
;
Jiulai TANG
- Publication Type:Journal Article
- Keywords:
Hereditary spastic paraplegia;
Gene;
Heredity;
Mutation
- From:
International Journal of Pediatrics
2010;37(6):622-624
- CountryChina
- Language:Chinese
-
Abstract:
There are twenty-one gene-associated sites of hereditary spastic paraplegia (HSP) that have been reported, including eleve gene-associated sites of autosomal dominant inheritance, seven gene-associated sites of autosomal recessive and three gene-associated sites of X2 linked recessive. Nine genes of HSP have been cloned as followed, atlastin, spastin, paraplegin, L1CAM, PLP, Hsp60, maspardin, TRAK1 and so on.
