Optimizing the conditions for extraction of Daoguleebusi-7 capsule by orthogonal experiments
10.3760/cma.j.issn.1673-4246.2010.06.034
- VernacularTitle:用正交试验设计优选苦参七味胶囊的提取工艺条件
- Author:
Yongmei MENG
;
Eerdemutu HAN
;
Genduxi MENG
- Publication Type:Journal Article
- Keywords:
Daoguleebusi-7 capsule;
Orthogonal Experiments Design;
HPLC;
Extraction process
- From:
International Journal of Traditional Chinese Medicine
2010;32(6):535-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the optimal conditions for extraction of Daoguleebusi-7 capsule. Methods A comprehensive investigation for the process of extraction by water and ethanol was made using orthogonal experiments.Results The optimal process conditions were: gardenia and another drug were added into 12 volumes of water, extracted 2 times and two hours per time; Sophorae Flavescentis and other four dugs were added into 12 volumes of 85% ethanol,extracted 3 times and two hours per time, elecampane was crushed and screened through 100 mesh sieve to electuary.Conclusion The extraction process is simple and feasible for operation.
