Progress on the association between respiratory viral infections during early-life and asthma attack in later childhood
10.3760/cma.j.issn.1673-4408.2010.06.012
- VernacularTitle:婴幼儿期病毒感染与儿童期哮喘的关系研究进展
- Author:
Wei CHEN
;
Yubo CAI
- Publication Type:Journal Article
- Keywords:
Viral infection during early-life;
Childhood asthma;
Epigenetics
- From:
International Journal of Pediatrics
2010;37(6):585-587
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory viral infections are the most common cause of infantile wheezing, as well as one of the major inducents of acute exacebarbations of chronic childhood asthma. Recent studies focus on the mechanism of virus-induced airway inflammatory response which is still not completely clear. Many new pathophysiologic mechanisms such as epigenetics are advanced to explain the association between viral respiratory infections and asthma attack. In the present reports, recent data on the role of early-life viral infections in the development and progression of childhood asthma are reviewed.