Effect of initial treatment protocol on prognosis of pneumonia in the kidney transplant recipients
10.3760/cma.j.issn.0254-1785.2010.11.005
- VernacularTitle:早期强化治疗对肾移植后并发肺炎预后的影响
- Author:
Xiaojun WU
;
Tianpeng WU
;
Changping YU
;
Qingquan LI
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Pneumonia;
Treatment protocols;
Prognosis
- From:
Chinese Journal of Organ Transplantation
2010;31(11):657-660
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of different initial treatment protocols on the prognosis of pneumonia in the kidney transplant recipients. Methods Sixty-seven cases of pneumonia following kidney transplantation were divided into case group (34 cases) and control group (33 cases).The patients in case group were treated with Imipenem and Cilastatin, SMX/TMP and ganciclovir,and those in control group received routine treatments. Mortality and length of stay in hospital (LOS)were analyzed. Results Mortality (5.9 % ) and LOS (15 days) in case group were reduced as compared with those in control group ( 18. 2 %, 23 days, respectively) (P＜ 0. 05). Among the patients without severe pneumonia, the mortality and incidence of LOS beyond 21 days in case group (3. 4 %, 1/29; 3. 4 %, 1/29) were lower than those in control group (17. 2 %, 5/29; 37. 9 %, 11/29, respectively) (P＜0. 05). Whether the patients were admitted to hospital sooner or later, the incidence of LOS beyond 21 days in case group was lower than that in control group (P＜0. 05).Whether the etiologies were determined or undetermined, the incidence of LOS beyond 21 days in case group was lower than that in control group (P＜0. 05). The incidence of LOS beyond 21 days in case group was lower than that in control group among the patients with cardiopulmonary disease (P＜0. 05). Conclusion The initial appropriate treatment would improve the prognosis of pneumonia in the kidney transplant recipients.
