Analysis of clinical characteristics of benign prostatic hyperplasia and the correlation between BPH and cardivascular diseases in the elderly

VernacularTitle:老年人良性前列腺增生与心血管疾病的关系
Author: Jie CAO ; Haiya WANG ; Ningyuan FANG
Publication Type:Journal Article
Keywords: Prostatic hyperplasia; Cardiovascular diseases
From: Chinese Journal of Geriatrics 2010;29(11):894-895
CountryChina
Language:Chinese
Abstract: Objective To realize the clinical characteristics and treatment strategies in elderly patients with benign prostatic hyperplasia (BPH), and investigate the correlation between severity of BPH and cardiovascular diseases. Methods One hundred consecutively referred patients with BPH were enrolled in this study, and the international prostate symptom score (IPSS) and quality of life (QOL) scores were recorded. All patients were queried in detail about history of cardiovascular disease, and underwent detection of prostate specific antigen (PSA) levels, prostate volume (PV)measurement by abdominal ultrasound. Results PV and serum PSA level increased with age.Forty-eight percent of patients had a moderately enlarged prostate (IPSS 8-19). Patients with BPH had higher incidence of hypertension, diabetes, as well as coronary artery disease (P＜0.05). The most common medical treatments were 5α-reductase inhibitors and a-receptor blockers in our hospital and most patients had good compliance. Conclusions The severity of BPH is correlated with age and morbidity of coronary artery disease. For the drug intervention therapy, 5a-reductase inhibitors have the highest utilization rate.