Progress in minipuberty and early diagnosis of sexual abnormality diseases
10.3760/cma.j.issn.1673-4408.2010.06.028
- VernacularTitle:小青春期与性发育异常疾病早期诊断的研究进展
- Author:
Ruifang WANG
- Publication Type:Journal Article
- Keywords:
Minipuberty;
Sexual abnormality diseases;
Early diagnosis
- From:
International Journal of Pediatrics
2010;37(6):634-636
- CountryChina
- Language:Chinese
-
Abstract:
The transient surge in the hypothalamic GnRH pulse generator-pituitary gonadotropin-gonadal apparatus,sometimes called the minipuberty of early infancy, is associated with special secretion pattern of many sex hormones. This period is thought to be an important stage for sex development, and provides clinicians early evidences to diagnose sexual abnormality diseases. This review summarizes the formation and characteristic of minipuberty,and the mechanism of its abnormal hormone secretion leading to sexual abnormality, and thus focus on the value of minipuberty for early diagnosis of sexual abnormality diseases.