Recent advances of thymic stromal lymphopoietin in respiratory tract infection
10.3760/cma.j.issn.1673-4408.2010.06.014
- VernacularTitle:胸腺基质淋巴细胞生成素在呼吸道感染中的作用
- Author:
Xiaoqing LI
;
Jianhong GONG
- Publication Type:Journal Article
- Keywords:
Thymic stromal lymphopoietin;
Infection;
Inflammation;
Respiratory tract;
Immune
- From:
International Journal of Pediatrics
2010;37(6):591-593
- CountryChina
- Language:Chinese
-
Abstract:
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine. TSLP exerts a profound influence on the polarization of dendritic cells and T helper2 cytokine production. TSLP also directly promotes T-cell proliferation in response to T-cell receptor activation and Th2 cytokine production. TSLP affects different populations of cells,indicative of the broad role of TSLP in the regulation of respiratory tract infected and inflammatory processes.
