Progress of staphylococcal cassette chromosome mec in methicillin-resistant Staphylococcus aureus
10.3760/cma.j.issn.1673-4408.2010.06.034
- VernacularTitle:耐甲氧西林金黄色葡萄球菌可移动基因元件——SCCmec的研究进展
- Author:
Yingchao LIU
- Publication Type:Journal Article
- Keywords:
MRSA;
SCCmec;
Mec complex;
ccr complex;
Detection methods
- From:
International Journal of Pediatrics
2010;37(6):651-654
- CountryChina
- Language:Chinese
-
Abstract:
Staphylococcus aureus can cause a broad variety of infections, ranging from minor infections of the skin to serious necrotic pneumonia. Pathogenicity and high degree of multi-drug resistance are the characteristics of the methicillin-resistant Staphylococcus aureus ( MRSA ). The cause of resistance to methicillin and all other β-lactam antibiotics is the mecA gene, which is situated on a mobile genetic element, the staphylococcal cassette chromosome mec (SCCmec). Eight major variants of SCCmec, type Ⅰ to Ⅷ, are distinguished. This paper describes the structure and typing of SCCmec, its discovery, detection methods and distributiong are reviewed.
