Clinical and pathologic features of xanthogranulomatous cystitis

VernacularTitle:黄色肉芽肿性膀胱炎的临床与病理特点分析
Author: Gang ZHANG ; Changli WU ; Hailong HU ; Yi WANG
Publication Type:Journal Article
Keywords: Cystitis; Xanthogranuloma; Diagnosis; Pathology
From: Chinese Journal of Urology 2010;31(11):767-769
CountryChina
Language:Chinese
Abstract: Objective To review the clinical and pathologic features of xanthogranulomatous cystitis (XC). Methods The clinical and pathologic data of 3 patients (2 females and 1 male, mean age, 37.3 year, age range, 24-50 year) with XC were reported in combination with review of the relevant literature. All 3 cases had recurrences cystitis-like symptoms, 2 cases had lower abdominal pain.1 case found low abdominal palpable mass during physical examination. Ultra sonography and CT revealed solid mass at the dome of the bladder. Partial cystectomy was performed on 2 patients, the rest 1 was case treated as urachal carcinoma.Results Postoperative pathology confirmed XC. Pathological features were as follows: xanthoma cells (lipidladenmacrophages), multinucleated giant cells and cholesterol clefts. With 12-36 (mean 28) months follow-up, there was no recurrence and cystitis-like symptoms on these patients. Conclusions XC is a rare disease. XC is usually identified by pathology. The presence of a concomitant neoplasm should be considered when the diagnosis of XC is made.Surgical resection could be a curative treatment.