Screening for thyroid diseases during pregnancy to protect the brain development of offspring
10.3760/cma.j.issn.1000-6699.2010.11.001
- VernacularTitle:倡导妊娠期甲状腺疾病筛查,保护后代智力发育
- Author:
Zhongyan SHAN
;
Weiping TENG
- Publication Type:Journal Article
- Keywords:
Pregnancy;
Subclinical hypothyroidism;
Brain development;
Offspring
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(11):913-915
- CountryChina
- Language:Chinese
-
Abstract:
Studies from clinical observation and animal experiments have indicated that maternal subclinical hypothyroidism during the first gestational term may lead to impairment of brain development of offspring, and early diagnosis and effective treatment may prevent the damage. Therefore, we suggest that it is pertinent to screen thyroid function before gestational 8 weeks in pregnant women, especially for those who have risk factors of thyroid diseases. We also suggest that maternal subclinical hypothyroidism should be treated with levo-thyroxine ( L-T4 ) before 12 gestational weeks. Thyroid function should be measured regularly in order to adjust the dosage of L-T4 and reach the goal of treatment on time, so as to protect the brain development of fetus and offspring.
