Clinical analysis of 5 cases of duodenal gastrointestinal stromal tumors
10.3760/cma.j.issn.1007-8118.2010.11.014
- VernacularTitle:十二指肠间质瘤五例临床分析
- Author:
Guoxiang ZHANG
;
Zhi DU
;
Yijun WANG
;
Fuhua NIE
;
Qiang YUAN
;
Wei SUN
;
Guiming SHU
- Publication Type:Journal Article
- Keywords:
Duodenal neoplasms;
Stromal tumor
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(11):839-841
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the features of clinical diagnosis and treatment of duodenal gastrointestinal stromal tumors(GIST).Methods Retrospective analysis was performed on clinical data of 5 cases of duodenal GIST treated in our hospital between April 2002 and May 2009.Results The duodenal GIST was mainly located in the 2nd(3/5)and 3rd portion of duodenum(2/5).Clinical diagnosis of the disease mainly depended on barium meal examination, gastrointestinal endoscopy, and CT scanning.Two patients were treated with pancreaticoduodenectomy, 1 with segmental duodenectomy and 2 with local resection.After operation, 2 patients had recurrence and 1 of them underwent adjuvant therapy with Gleevec.Conclusion Surgical resection is the only effective therapeutic method for duodenal GIST.Various surgical procedures are mainly determined by the location and size of the tumors.For patients with a high degree of pathologic grade, adjuvant therapy with Gleevec is necessary.
