An experimental study on place reaction of support drainage tube in cholecystojejunostomy

VernacularTitle:支撑引流管在胆肠吻合中置放反应的实验研究
Author: Zuosheng FAN ; Shilin SUN ; Jie LI ; Changcheng QIU ; Hongwei ZHAO ; Tao GAO ; Sheng WANG ; Bo ZHANG ; Kaifu LI ; Yanmin ZHANG
Publication Type:Journal Article
Keywords: Cholecystojejunostomy; Support tube; Experimental study
From: Chinese Journal of Hepatobiliary Surgery 2010;16(11):845-847
CountryChina
Language:Chinese
Abstract: Objective To investigate the place reaction of support drainage tube in cholecystojejunostomy and its pathological changes.Methods Eight pigs were randomized into 2 groups.The tube-placing cholecystojeunostomy(n=2)or choledochocholedochostomy(n=2)and non-tube-placing cholecystojejunostomy(n=2)or choledochocholedochostomy(n=2)were performed respectively.All the 8 pigs were sarcrificed 3 months after the operation for pathological examination.Results Gross anatomy catheter group showed anastomotic inflammatory hyperplasia, wall hardening hyperplasia,luminal narrow contracture and stone formation.Microscopic biopsy showed bile duct mucosa in interstitial lymphocytes, plasma cells and other chronic inflammatory cell infiltration, a large number of fibrous tissue hyperplasia.However, these features were not found in pigs without placing the tube.Conclusion The tube can not prevent the stenosis.It might promote the formation of stricture since it can stimulate inflammatory hyperplasia and tissue hardening.