The detection of cytokines in porcine-human mixed lymphocyte culture
- VernacularTitle:猪-人混合淋巴细胞培养中细胞因子的检测
- Author:
Chuansen SHAO
;
Yongliang SUN
- Publication Type:Journal Article
- Keywords:
Leukocyte culture test,mixed;
Cytokine;
Transplantation,heterologous
- From:
Chinese Journal of Organ Transplantation
1997;18(3):158-160
- CountryChina
- Language:Chinese
-
Abstract:
In order to explore the relationship between xenograft rejection and cytokines, the proliferative responses and cytokine contents from human lymphocyte were detected in porcinehuman mixed lymphocyte culture (MLC) and compared with human allo-MLC. The results showed that the proliferative responses in the former was equal to or stronger than that in the latter, and the kinetics of IL-2 and IFN-Y in both supernatants were similar but the peak of IL-4 from the former was higher than that from the latter (P<0.05). This suggests that cytokines are likely to play roles in porcine-human MLC.
