Relationship between tumor differentiation and related pathologic factors in Esophago-gastric junction adenocarcinoma
10.3760/cma.j.issn.1008-6315.2010.11.025
- VernacularTitle:食管-胃结合部腺癌肿瘤分化程度与相关病理学因素的关系
- Author:
Hongdan ZHANG
;
Yanhai CUI
;
Songxi XIE
;
Yi PAN
;
Zijun ZENG
;
Yingru LIN
;
Weixiong LI
- Publication Type:Journal Article
- Keywords:
Tumor of digestive tract;
Differentiation;
Vessel carcinoma embolus
- From:
Clinical Medicine of China
2010;26(11):1189-1191
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the tumor differentiation and the related pathologic factors in Esophago-gastric junction adenocarcinoma. Methods The pathological data from 163 patients of Esophago-gastric junction adenocarcinoma underwent radical surgical resections were randomly divided two groups (group1: well-differentiated,group2: poor-differentiated). The composition of N stages,T stages,morphological type and vessel carcinoma embolus were compared between the two groups ,respectively. The tumor sizes and the number of metastases lymph nodes were compared between the two groups. Results The cases with lower N stages or T stages in group1 were dominant(T1 and T2:55. 74%,N1 and N2:75.41%). Oppositely,those with higher N stages or T stages were dominant(T3 and T4:59.81%,N1 and N2:57.85%)in group 2. The differences were significant Incidence of vessel carcinoma embolus was 44. 26%(27/61)in group 1 and 63. 73%(65/102)in group 2,with a significant difference. There was no significant difference for morphological type in the two groups. The tumor sizes and the number of metastases lymph was 4. 27 ±2. 00 cm and 4. 15 ±5.27 respectively in group 1 ,and 5. 87 ± 3. 26 cm and 8. 80 ± 7.65 respectively in group 2. The differences were significantly different(Ps < 0. 01).Conclusions The tumor differentiation has significant effect on N stages,T stages,vessel carcinoma embolus,tumor size and the number of metastases lymph nodes in Esophago-gastric junction adenocarcinoma.