Advances in thyroid hormone transporters
10.3760/cma.j.issn.1000-6699.2010.11.028
- VernacularTitle:甲状腺激素转运体的研究进展
- Author:
Xiaochun TENG
;
Weiping TENG
- Publication Type:Journal Article
- Keywords:
Thyroid hormone transporters;
Organic anion transporting polypeptide 1C1 (OATP1C1);
Monocarboxylate transporter 8 (MCT8);
Monocarboxylate transporter 10 (MCT10)
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(11):1013-1016
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid hormones play important roles in growth, development, and metabolism of various cells and tissues. It has been assumed for a long time that thyroid hormones are lipophilic and enter cells by passive diffusion, but it has become increasingly clear that cellular uptake and efflux of thyroid hormones are mediated by transporters. The discovery of these thyroid hormone transporters will lead to a better understanding of the tissuespecific regulation of thyroid hormones.
