Severe acute pancreatitis complicating deep fungal infection: a report of 32 cases

VernacularTitle:重症急性胰腺炎合并深部真菌感染32例临床分析
Author: Hui XU ; Zhaoyang WU ; Lukun DUO ; Bakery AIHEMATE
Publication Type:Journal Article
Keywords: Pancreatitis,acute necrotizing; Infection; Fungi
From: Chinese Journal of General Surgery 2010;25(11):886-888
CountryChina
Language:Chinese
Abstract: Objective To investigate the characteristics and prevention of deep fungal infection (DFI) complicated by severe acute pancreatitis (SAP). Methods Clinical data of 135 SAP cases admitted from Oct. 1998 to Oct. 2009 were studied, the prevention and management of SAP with DFI ( 32cases) were investigated, among them there were 19 males and 13 females. Results Seven patients (21.9%) died of these 32 cases. The SAP patients with DFI were of more critical condition, longer course and having to stay in ICU about (21±6) d, most needed surgical debridement, on long-term indwelling catheters, intubation and mechanical ventilation, parenteral nutrition, long-term use of broad-spectrum antibiotics. These patients remained in the hospital for about (78 ± 14) d. Conclusions DFI is a common complication in SAP cases causing a significant mortality hence necessitating comprehensive prevention and control measures such as proper handling of the original disease, aseptic operation, prophylactic antibiotics and antifungal agents, which can reduce the incidence and mortality of SAP with DFI.