CT characteristics of thoracoabdominal localized Castleman disease
10.3760/cma.j.issn.1005-1201.2010.11.012
- VernacularTitle:胸腹部局限性Castleman病的CT特征分析
- Author:
Rengui WANG
;
Meng HUO
;
Dandan WANG
;
Li GAO
;
Weihong ZHANG
;
Wei SONG
;
Hongwei CHI
;
Caiying LI
;
Yuexiang ZHU
;
Huaiyou BIN
;
Nan LI
;
Yujun DONG
;
Jia NA
;
Ruie FENG
;
Yisheng WANG
;
Xuejun ZHU
- Publication Type:Journal Article
- Keywords:
Giant lymph node hyperplasia;
Thorax;
Abdomen;
Tomography,X-ray computed
- From:
Chinese Journal of Radiology
2010;44(11):1161-1166
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the CT characteristics of thoracoabdominal localized Castleman disease (LCD) in 55 cases and correlate with histopathologic features. Methods Fifty-five patients with LCD proved histopathologically in thorax ( n = 25 ) and abdomen ( n = 30 ) were collected during past 20 years. The unenhanced and contrast-enhanced CT were performed in all patients. Two radiologists reviewed CT images and the CT findings were analyzed simultaneously. Results In 54 patients with hyaline-vascular type ( n = 50 ) and mixed type ( n = 4 ) localized CD, the lesion typically presented as solitary mass (90. 7% , 49 cases), with irregular or lobular or infiltrative margin ( 83.3% , 45 cases),central calcification (38. 9%, 21 cases), marked enhancement (100% , 54 cases), focal non-necrosis low attenuation areas (72. 2%, 39 cases), lymphadenopathy (70.4%, 38 cases) and dilated feeding vessels adjacent to the mass (96.3%, 52 cases). One lesion with plasma cell type localized CD presented as a mass with irregular margin, mild enhancement and central necrosis. Four morphologic patterns wereclassified on CT, including solitary mass with well-circumscribed margin (n =4), irregular or lobular margin ( n = 30), infiltrative or halo-like margin ( n = 16 ), and multiple coalescent maasses ( n = 5 ). Conclusion CT features of thoracoabdominal localized CD are closely related to the location and pathological type. LCD with hyaline-vascular and mixed type has typical CT characteristics, while LCD with plasma cell type has no typical CT findings.
