EGFR targeted inhibitors in esophageal cancer
10.3760/cma.j.issn.1673-422X.2010.12.014
- VernacularTitle:表皮生长因子受体靶向抑制剂在食管癌中的应用
- Author:
Xiaojiang SUN
;
Yaping XU
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Receptor,epidermal growth factor;
Targeted therapy
- From:
Journal of International Oncology
2010;37(12):922-925
- CountryChina
- Language:Chinese
-
Abstract:
Overexpression of epidermal growth factor receptor (EGFR) in esophageal cancer has been related to tumor grade, vascular invasion and metastasis. The level of EGFR expression may be a predictive marker of esophageal caneer's sensitivity to chemoradiotherapy. EGFR inhibitors have been indicated as an effective targeted therapy, and promising results have been observed in phase Ⅱ and Ⅲ clinical trials.
