Molecular targeted therapy for carcinoma based on Notch signal transduction pathway
10.3760/cma.j.issn.1673-4203.2010.11.013
- VernacularTitle:Notch信号转导通路与肿瘤分子靶向治疗研究进展
- Author:
Hui ZHANG
;
Yingjiang YE
;
Shan WANG
- Publication Type:Journal Article
- Keywords:
Notch;
Signal transduction;
Neoplasms;
Molecular targeted therapy
- From:
International Journal of Surgery
2010;37(11):756-759
- CountryChina
- Language:Chinese
-
Abstract:
The Notch signaling pathway represents control cell proliferation, differentiation and apoptosis during development.Aberrant activation of this pathway contributes to tumorigenesis and genes in the Notch signaling pathway could be potential therapeutic targets.This review involves regulation of Notch pathway and molecular targeted therapy.
