Progress of research on relationship between gene p16 and lung cancer
10.3760/cma.j.issn.1673-422X.2010.11.016
- VernacularTitle:p16基因与肺癌关系研究进展
- Author:
Ping XIAO
;
Jianrong CHEN
- Publication Type:Journal Article
- Keywords:
Genes,p16;
Lung neoplasms;
Mythlation;
Gene therapy
- From:
Journal of International Oncology
2010;37(11):852-855
- CountryChina
- Language:Chinese
-
Abstract:
p16 tumor suppressor gene plays an important role in early diagnosis for lung cancer. The occurrence of lung cancer is closed associated with p16 gene aberrant methylation in promotor, seconed exon homozygous deletion, gene point mutation , lose of protein and mRNA expression. Also p16 is related to gene therapy and drug target therapy. This review will summarize the relationship between p16 and lung cancer.
