Expression of chlamydia pneumoniae DNA in peripheral blood in patients with atherosclerosis obliterans
10.3760/cma.j.issn.1008-6315.2010.11.013
- VernacularTitle:动脉硬化性闭塞症患者肺炎衣原体DNA的表达
- Author:
Wei ZHU
;
Huan SHEN
;
Dandan ZHAO
;
Tiezhu ZHAO
- Publication Type:Journal Article
- Keywords:
Chlamydia pneumoniae;
Atherosclerosis obliterans
- From:
Clinical Medicine of China
2010;26(11):1160-1161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between chlamydia pneumoniae(Cpn)and atherosclerosis obliterans(ASO). Methods Sixty ASO patients and 40 healthy persons were selected,and their Cpn DNA expressions in venous blood determined by polymerase chain reaction(PCR). Results The ASO patients had significantly higher positive expression rate of Cpn DNA than that of healthy persons(78. 33% vs. 47.50% ,P ＜0.05). In all 60 cases the Cpn DNA expressions were positively correlated with the severity of ASO. Conclusions Cpn DNA expression closely relates with ASO severity,and it plays an important role in the ASO pathogenesis.
