Analgesic efficacy of intravenous administration of lidocaine in patients after laparoscopic cholecystectomy
10.3760/cma.j.issn.0254-1416.2010.06.021
- VernacularTitle:腹腔镜胆囊切除术后患者静脉输注利多卡因的镇痛效果
- Author:
Yanmei ZHOU
;
Wengang JIAO
;
Xiangmo YAN
- Publication Type:Journal Article
- Keywords:
Lidocaine;
Infusions,intravenous;
Analgesia;
Cholecystectomy,laparoscopic
- From:
Chinese Journal of Anesthesiology
2010;30(6):698-699
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the analgesic efficacy of intravenous administration of lidocaine in patients following laparoscopic cholecystectomy. Methods Twenty-five ASA Ⅰ or Ⅱ patients, aged 30-55 yr,weighing 50-70 kg, scheduled for laparoscopic cholecystectomy, were enrolled in this study. Lidocaine 1.5 mg/kg was injected intravenously immediately before anesthesia. Anesthesia was induced with intravenous fentanyl 2 μg/kg, propofol 2 mg/kg and rocuronium 1 mg/kg and maintained with inhalation of isoflurane (end-tidal concentration 1.5%-2.0%) and intermittent iv boluses of rocuronium after tracheal intubation. Lidocaine was infused abdominal intravenously at a rate of 1.5mg·kg-1·h-1 form the end of ofperation to 24 h after operation. The degree of abdominal pain and shoulder pain was assessed with VAS score at 1, 6, 12 and 24 h after operation. The effective analgesia was defined as VAS score of ≤ 3. The adverse reactions were recorded. Results The effective analgesia rate was 100% within 24 h after operation. No adverse reactions occurred. Conclusion Intravenous administration of lidocaine exerts satisfactory analgesia in patients after laparoscopic cholecystectomy.
