Progress of interleukin-24 in cancer therapy research
10.3760/cma.j.issn.1673-422X.2010.12.007
- VernacularTitle:白细胞介素24抗肿瘤治疗的研究进展
- Author:
Kai ZHANG
;
Guan JIANG
- Publication Type:Journal Article
- Keywords:
Interleukins;
Neoplasms;
Genes
- From:
Journal of International Oncology
2010;37(12):900-902
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-24 (IL-24) is a novel cancer suppressor cytokine. It can suppress cancer cell growth, induce cancer cell apoptosis, inhibit angiogenesis, stimulate the PBMC secretion of cytokines, and enhance the antitumor activity of radiotherapy, chemotherapy and targeting gene-virotherapy. It is reasonable to suggest that IL-24 may be a powerful and effective protocol for combinatorial cancer treatment in the clinic.
