Influence factors of surgical treatment for left colorectal carcinoma with acute colorectal obstructive

VernacularTitle:手术治疗左半大肠癌并急性肠梗阻预后影响因素分析
Author: Jiankang XU ; Qingan FANG
Publication Type:Journal Article
Keywords: Colorectal neoplasm; Intestinal obstruction; Prognosis; Influence factors
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(21):2963-2965
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of surgical treatment in left colorectal carcinoma with acute colorectal obstructive.Methods Clinical data of 70 patients with acute left obstructive colorectal carcinoma treated by emergent operation were collected.65 cases received one stage tumor resection and 5 cases received two stage tumor resection were retrospectively analyzed.Results The complication rate was 20.0%(14/70),mortality rate was 1.0%(1/70);radical surgery after 1,3,5-year cumulative survival rates were 100.0%,93.6%,66.7% wich were higher than the palliative surgery 69.2%,0.0%,0.0%(all P＜0.01);With univariate analysis,radical resection,Dukes stage,tumor differentiation,and chemotherapy were found to be significant factors associated with the overall survival(χ2 = 16.546,20.649,5.953,all P＜0.01);with the overall survival.With multivariate analysis,radical resection independently affected the overall survival(Wald = 5.877,P＜0.01).Conclusion One stage radical resection was feasible for left obstructive colorectal carcinoma,and could improve survival rate after operation.