Application of time intensity curve of contrast enhanced ultrasound in the discrimination of benign and malignant soft tissue tumors
10.3760/cma.j.issn.1004-4477.2010.11.022
- VernacularTitle:良、恶性软组织肿块超声造影表现分析
- Author:
Xiaoning LIANG
;
Ruijun GUO
;
Lihuan GONG
;
Ying ZHANG
;
Zhaoxia ZHONG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Soft tissue neoplasms
- From:Chinese Journal of Ultrasonography
2010;19(11):981-983
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of time intensity curve of contrast enhanced ultrasound in the discrimination of benign and malignant soft tissue tumors. Methods Thirty-seven cases of soft tissue tumors were carried out contrast-enhanced ultrasound examination. The region of interest in the dynamic images were chosen to carry out Gamma-Variate curve fitting through Q-LAB software and made a quantitative analysis. Then they were compared with pathological diagnosis to analyze the ultrasound imaging performance of benign and malignant tumors and their characteristics of micro-irrigation. Results Thirty-seven cases of soft tissue tumors were pathologically diagnosed 21 cases of benign and malignant in 16 cases. The perfusion of benign tumors were mainly uniformity (19/21) or potentialization (2/21). The perfusion of malignant tumors were mainly uniformity (10/16) or nonuniformity (6/16). There were no significant differences in time to peak(TTP) and arrival time of contrast agent(AT) between benign and malignant tumors( P ＞0.05). The upslope rate(A) and the derived peak intensity(DPI) in benign group were significantly less than malignant group ( P ＜0.05). Conclusions Time-intensity curve analysis of contrast-enhanced ultrasound showed that benign and malignant soft tissue tumors were different in perfusion,and it will be of a certain value for the clinical differential diagnosis.
