Early pathological morphology and clinical significance of perforated duodenal ulcer closed after non-surgical treatment
10.3760/cma.j.issn.1673-4904.2010.32.006
- VernacularTitle:十二指肠溃疡穿孔非手术闭合后早期病灶形态与临床意义
- Author:
Gang CHEN
;
Donghui ZHANG
;
Changjing ZHENG
;
Shicheng TAN
;
Gang LU
;
Yexing LIU
;
Jianbao ZHANG
;
Junda LI
;
Qun HUANG
- Publication Type:Journal Article
- Keywords:
Peptic ulcer;
Gastroscopy;
Perforation closed;
Non-surgical treatment;
Early pathological manifestations
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(32):15-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research early pathological morphology and clinical significance of perforated duodenal ulcer (PDU) closed after non-surgical treatment. Methods Observed morphological changes of duodenal ulcer (DU) lesion with gastroscopy for 302 patients of PDU with non-surgical treatment in early period,when the perforation closed and measured up the clinical indicators during this hospitalization.Results There were 255 patients to be diagnosed with DU caused the perforation. These lesions were characteristic and shown the PDU closed at the bottom and the deep concave ulcers, except for 1 case which complicated by duodenal fistula. These ulcer types were diverse according to the time difference after treatment. No case of re-perforated ulcers or recurrence of peritonitis caused by gastroscopy. Conclusions Deep concave ulcer with A1 phase mainly is an early pathological manifestations of the DU after treated the PDU with non-surgical method characteristically. The wall of the closure of the serosal side is an original form closed perforated ulcer by non-surgical treatment. The risk of perforation associated with the following factors:( 1 )A single DU is located in the anterior wall region. (2)The shape of two kissing DU. (3)The diameter of DU ≥ 1.1 cm. In this case,early diagnosis by using endoscopy is a safe way.
