Cytokeratin 8 and cancer
10.3760/cma.j.issn.1673-422X.2010.12.004
- VernacularTitle:细胞角蛋白8与肿瘤
- Author:
Jinghui YAO
- Publication Type:Journal Article
- Keywords:
Keratins;
Protein processing,post-translational;
Neoplasms;
Neoplasm metastasis
- From:
Journal of International Oncology
2010;37(12):892-894
- CountryChina
- Language:Chinese
-
Abstract:
Cytokeratin 8 ( CK8 ) belongs to the keratin family of intermediate filament cytoskeletal proteins. A lot of researches have demonstrated that abnormal expression or post-translational modifications of CK8 may affect its activity and consequently affect the development and progression of tumors. Therefore, investigating the role of CK8 in tumorigenesis may contribute to the prevention and treatment of tumors.
