Cancer-testis antigens and lung cancer
10.3760/cma.j.issn.1673-422X.2010.12.012
- VernacularTitle:肿瘤-睾丸抗原与肺癌
- Author:
Ying XU
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Antigens;
Immunotherapy
- From:
Journal of International Oncology
2010;37(12):916-919
- CountryChina
- Language:Chinese
-
Abstract:
Cancer-testis antigens (CTAs) are protein antigens with normal expression restricted to adult testis and yet are aberrantly activated and expressed in a proportion of various types of tumor tissues. The expressions of CTA correlate with tumor staging, histopathological subtype, recurrence and metastasis in nonsmall cell lung cancer. CTAs are immunogenic in lung cancer patients and have a good prospect in lung cancer Immunotherapy.
