Ribozymes and deoxyribozymes in targeted cancer therapy
10.3760/cma.j.issn.1673-422X.2010.12.003
- VernacularTitle:核酶和脱氧核酶靶向治疗肿瘤的研究进展
- Author:
Yanyan REN
- Publication Type:Journal Article
- Keywords:
Ribonucleases;
Deoxyribonucleases;
Neoplasms
- From:
Journal of International Oncology
2010;37(12):889-892
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, with the introduction of novel vectors capable of highly efficient transduction ,ribozymes and dexyribozymes have been become an ideal approach to anticancer therapy due to their high efficiency and lack of severe adverse effects. As many high efficiency targets have been found for cancer therapy, targeted therapy using ribozymes and deoxyribozymes may have multiple effects such as induction of tumor apoptosis and inhibition of tumor growth, metastasis, and angiogenesis.
