Relationship between B-type natriuretic peptide and outcome of non-cardiac critically ill elderly patients in emergency intensive care unit

VernacularTitle:重症监护病房老年非心原性危重症患者B型利钠肽水平与预后的关系
Author: Guoqiang ZHANG ; Yongkang TAO ; Rui LIAN ; Jianping YANG ; Wen GAO ; Zhi ZHANG ; Suqiao ZHANG ; Shuiping ZHAO
Publication Type:Journal Article
Keywords: Natriuretic peptide,brain; Critical illness; Prognosis
From: Chinese Journal of Geriatrics 2010;29(12):969-972
CountryChina
Language:Chinese
Abstract: Objective To explore the prognostic value of B-type natriuretic peptide (BNP) for 28-day mortality of elderly patients with non-cardiac critical ill in emergency intensive care unit (EICU). Methods A total of 70 elderly non-cardiac critically ill patients (age≥60 years) in EICU were enrolled, and the blood samples were collected to detect BNP level after the patients' admission to EICU. After 28 days, the mortality was assessed. Results Twenty-two patients (31.4 %) died during 28 days observation, whose BNP levels were significantly higher than that of the survivors [ln BNP: (6.4 ± 1.2) ng/L vs. ( 5. 1 ± 1.5 ) ng/L, P＜ 0. 05] ; BNP level had an area under the receiver operating characteristic curve of 0. 759 (95% CI: 0. 636-0. 882, P＜0.05) for predicting mortality,and the optimal cut point of BNP was 342 ng/L (sensitivity 77.3%, specificity 68.7%).Conclusions BNP level could be a predictor for 28-days mortality for elderly non-cardiac critically ill patients.