The new development in genetic studies of type 1 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2010.12.025
- VernacularTitle:1型糖尿病遗传学研究新进展
- Author:
Weihui YU
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 1;
Susceptibility loci;
Genome-wide association study;
Polymorphism,single nucleotide
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(12):1090-1093
- CountryChina
- Language:Chinese
-
Abstract:
Type 1 diabetes, a complex genetic disease, is determined by both genetic and environmental factors. After excluding the five susceptibility loci discovered by genetic linkage studies and candidate-gene association studies, more than 30 new susceptibility loci have been found to be related with type 1 diabetes as a result of genome-wide association study.