Study on the polysomnography of the patients with depression
10.3760/cma.j.issn.1674-6554.2010.11.009
- VernacularTitle:阻滞性与非阻滞性抑郁症患者睡眠脑电图研究
- Author:
Jingli GAN
;
Qiaoping CHEN
;
Huifeng DUAN
;
Dongwei ZHANG
- Publication Type:Journal Article
- Keywords:
Retardative depression;
Non-retardative depression;
Polysomnography
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2010;19(11):983-985
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the variations of polysomnography of the patients with retardative depression and non-retardative depression. Methods Twenty-eight patients with depression without any medicine at least for 1 month and fifteen normal controls were assessed in this study. Based on the scores of retardation of Hamilton Depression Scale( HAMD), the patients were divided into the group of retardative depression and the group of non-retardative depression. Polysomnography was given to all the subjects. Results Compared with the normal controls, the depressive patients both in the retardative depression group and in the non-retardative depression group showed significant differences of lower total sleep time (TST), sleep efficiency (SE), SWS% , rapid eye movement ) sleep time ( RT), REM sleep latency (RL) ( all P ＜ 0. 05 ), and higher sleep latency (SL) , awakening time( AT), awakening number( AN ), the percentage of AT( A/TST% ), the percentage of 1 sleep( S1 % ), the percentage of RT( RT% ), REM activity ( RA), and REM intensity (RI). REM density (RD) in the retardative depression group was significantly higher than both the non-retardative depression group and the control group ( t =2.36, P＜ 0. 05; t = 2.75, P＜ 0. 05 ). Conclusion Abnormalities of PSG in depression are proved, and RD may be relative to retardation. The differences of PSG do not existed between different kinds of depression such as retardative depression and non-retardative depression.
