Dynamic detection of C-reactive protein and procalcitonin to predict the occurrence of multiple organ dysfunction syndrome after multiple trauma

VernacularTitle:动态检测C反应蛋白及降钙素原预测多发伤后多器官功能障碍综合征的发生
Author: Jianguo WU ; Xuchao XUE ; Jianwei BI ; Guoen FANG
Publication Type:Journal Article
Keywords: C-reactive protein; Calcitonin; Multiple organ failure; Multiple trauma
From: Chinese Journal of Postgraduates of Medicine 2010;33(35):1-3
CountryChina
Language:Chinese
Abstract: Objective To investigate the relation of the peripheral blood C-reactive protein (CRP)and procalcitonin (PCT) and multiple organ dysfunction syndrome( MODS ) for patients with multiple trauma.Methods A total of 136 patients with multiple trauma were divided into MODS group (49 cases) and non MODS group (87 cases),and 50 healthy volunteers were chosen as control group. Peripheral blood CRP and PCT concentration were detected at different times. Results The highest concentration of peripheral blood CRP in MODS group was appeared on 48 h [(38.7 ± 2.7) mg/L], CRP concentrations in MODS group were significantly different with non MODS group and control group (P ＜0.05). The highest concentration of peripheral blood PCT in MODS group was appeared on 24 h [(20.3 ± 1.7)μ g/L], PCT concentrations in MODS group were significantly different with non MODS group and control group (P＜ 0.05). Conclusions CRP and PCT are relevant to the occurrence of MODS in trauma acute stage. The observation of peripheral blood CRP and PCT concentrations can predict the occurrence of MODS.