The Cytologic Features of Desmoplastic Small Round Cell Tumor with Intranuclear Inclusions : A Case Report .
- Author:
Ho Chang LEE
;
Hye Suk HAN
;
Ok Jun LEE
- Publication Type:Case Report
- Keywords:
Desmoplastic small round cell tumor;
Cytokeratin;
EWS-WT1 fusion protein;
Intranuclear Inclusions;
Cytology
- MeSH:
Desmoplastic Small Round Cell Tumor;
Female;
Forearm;
Humans;
Intranuclear Inclusion Bodies;
Keratins;
Young Adult
- From:Korean Journal of Pathology
2009;43(3):279-284
- CountryRepublic of Korea
- Language:English
-
Abstract:
Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm of young adults and it is characterized by polyphenotypic differentiation. We experienced a case of abdominal DSRCT that occurred in a 19-year-old female who presented with painful swelling of her right forearm. The tumor was cytokeratin-negative and it exhibited some tumor cells with intranuclear inclusions. Molecular demonstration of EWS-WT1 fusion transcripts is particularly useful to confirm the diagnosis of DSRCT without epithelial differentiation. We report here on a case of cytokeratin-negative DSRCT that showed an unusual feature of intranuclear inclusions.
