HCV re-infection and hepatitis C recurrence after liver transplantation
10.3760/cma.j.issn.1007-8118.2010.12.026
- VernacularTitle:肝移植术后丙型肝炎病毒的再感染与丙肝复发
- Author:
Qiuhong WANG
;
Jie HUANG
;
Daguang TIAN
;
Mingdao HU
;
Xiaoping WEI
;
Dongyun CUN
- Publication Type:Journal Article
- Keywords:
HCV recurrence;
Post-liver transplantation;
Sustained virological response
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(12):966-969
- CountryChina
- Language:Chinese
-
Abstract:
Different degrees of HCV re-infection exist in patients with hepatitis C after liver transplantation. Its pathogenesis is different according to different phases of the disease. Factors affecting its recurrence include HCV gene type, viral load, HLA matching between donor and recipient, time of recurrence, donor's age and so on, in which the application of immunosuppressants is the most important influencing factor. The virological response can be used to evaluate the effects of treatment. Now, it is widely accepted that the best choice and therapeutic plan is Pegy interferon alfa-2a/2b combined with Ribavirin.
