To determine the risk factors of renal dysfunction (RD) in open heart surgery under CPB
- Author:
Nguyen Quoc Kinh
- Publication Type:Journal Article
- Keywords:
Risk factors;
Renal dysfunction;
Open heart surgery
- MeSH:
Thoracic Surgery, Fanconi Syndrome, Risk Factors
- From:Journal of Medical Research
2005;34(2):63-67
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Material and methods: All patients with open heart surgery under CPB was enrolled in a case-control study. RD is defined as creatinine clearance <60 ml/min. 8 risk factors such as pre-operative RD, duration of CPB and of aortic clamping, core temperature, hematocrit, perfusion pressure, hemoglobinuria, use of vasopressors. Results: 5 independent risk factors of RD during CPB are perfusion pressure below 50 mmHg lasting over 30 min (adjusted OR 8.77), CPB time> 120 min (adjusted OR 6.35), aortic clamping >60 min (adjusted OR 4.16), pre-operative RD (adjusted OR 2.98), hemoglobinuria (adjusted OR 2.68). Conclusions: 5 independent risk factos of RD during CPB are long and low perfusion pressure, long duration of CPB and of aortic clamping, pre-operative RD and hemoglobinuria.
