Evaluation of the chemotherapy effect in advanced gastric carcinoma using double contrast-enhanced ultrasonography
10.3760/cma.j.issn.1004-4477.2010.12.012
- VernacularTitle:超声双重造影对进展期胃癌化疗疗效评价的初步研究
- Author:
Yanjuan TAN
;
Pintong HUANG
;
Ying CHENG
;
Rong HU
;
Kungao ZHAN
;
Liang WANG
;
Huiliao HE
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Stomach neoplasms
- From:
Chinese Journal of Ultrasonography
2010;19(12):1043-1046
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of double contrast-enhanced ultrasonography (DCUS) on evaluation of the chemotherapy effect in advanced gastric carcinoma. Methods A total of 21 patients with unresectable and received chemotherapy of advanced gastric carcinoma were examined using ultrasound after taking oral contrast agent and bolus injection of Sono Vue, and findings of DCUS of each patient before and after chemotherapy were compared. Results The thickness of lesions was slightly thinner than that after chemotherapy,but there was no significant difference ( P ＞0. 05). In addition, there was no significant difference in the basal intensity (BI), peak intensity (PI), arrive time (AT) and time to peak (TTP) of gastric carcinoma tissues after chemotherapy (P ＞0.05). While the enhanced intensity (EI) value of gastric carcinoma tissues after chemotherapy was significantly less than that before chemotherapy (P ＜0.05). Conclusions The EI value in gastric carcinoma tissues may be considered as a sensitive and effective index in assessing the therapeutic effect of the chemotherapy in patients with advanced gastric carcinoma.
