Comparison of consumption of drugs for patient-controlled intravenous analgesia in patients with different blood groups
10.3760/cma.j.issn.0254-1416.2010.09.002
- VernacularTitle:不同ABO血型病人自控静脉镇痛药物用量的比较
- Author:
Xu ZHU
;
Hui LU
- Publication Type:Journal Article
- Keywords:
ABO blood-group system;
Pain,postoperative;
Analgesia,patient-controlled;
Sufentanil
- From:
Chinese Journal of Anesthesiology
2010;30(9):1028-1029
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the consumption of the drugs for patient-controlled intravenous analgesia (PCIA) in patients with different blood groups. Methods One hundred female ASA Ⅰ or Ⅱ patients, aged 30-50 yr, body mass index ＜ 30 kg/m2 , scheduled for elective total hysterectomy or myomectomy, were enrolled in this study. The patients were divided into 4 groups according to the blood group: group A ( n= 25), group B ( n = 30), group AB ( n = 11 ) and group O ( n = 34). Patients received iv injection of flurbiprofen 30 min before the end of surgery and sufentanil at the end of surgery. PCIA with sufentanil 1.2 μg/ml ( bolus dose 2.0 ml, background infusion 0.5 ml/h, lockout interval 5 min) was performed when the VAS score ≤4. The loading dose and consumption on 1 st and 2nd day after operation for sufentanil were recorded. The adverse reactions were observed.Results The loading dose and consumption on 1st day after operation for sufentanil were the highest in group A and B, the second in group AB, and the lowest in group O among the 4 groups. Conclusion The consumption of the drugs for PCIA is different in patients with different blood groups.
